他发生了很大的变化英语怎么说

"He has undergone a significant change" 意思是 "他发生了很大的变化"。

"Undergo" 是一个动词，意思是 "经历，遭受"。"Significant" 是形容词，意思是 "重要的，显著的"。"Change" 是名词，意思是 "变化"。

例句：

He has undergone a significant change since the last time I saw him. 上一次见到他以来, 他已经发生了很大的变化。
The company has undergone a significant change in management. 公司管理层发生了重大变革。
The patient underwent a significant change in their condition after the surgery. 手术后病人病情发生了显著变化。